– Company also Secures Follow-on Order from Existing Contract Research Customer for Adoptive Cell Therapy (CAR T) Application –
Applied DNA Sciences, Inc. (NASDAQ: APDN) (“Applied DNA” or the “Company”), a leader in Polymerase Chain Reaction (PCR)-based DNA manufacturing, announced that it received orders for its linear DNA to be evaluated in an RNA vaccine and Adeno-Associated Virus (AAV) production from two new contract research customers, respectively. The Company also received a follow-on order for linear DNA from an existing contract research customer for a preclinical CAR T therapy. The follow-on order marks the third order from the existing customer for use across multiple applications. All orders are to be shipped by the end of calendar 2020.
Applied DNA’s unique large-scale PCR production of linear DNA is made capable by its LinearDNA™ platform, a proprietary process that enables large, gram-scale production of single- or double-stranded DNA for diagnostics; therapeutics, such as CAR T; vaccines, such as those made of RNA and DNA; and improves the agility of virus production, such as AAV. Some COVID-19 vaccines utilize AAV as the vector for delivery of a synthetic gene that causes the transfected cell to release antigens that promote immunity to SARS-CoV-2. The Company announced in August 2020 that it filed a new U.S. patent application for the manufacture of AAV via its LinearDNA™ platform.
“Our LinearDNA manufacturing platform is paving a new path for nucleic acid-based drug development that, to date, is largely reliant on plasmid-based production that is lengthy, prone to toxin contamination, promulgating antibiotic resistance, accidental inclusion of non-target DNA, and genomic integration. To our knowledge, we are the only company to pursue the commercialization of linear DNA for diagnostic and therapeutic applications via large-scale PCR. We believe this makes us applicable to every preclinical or clinical nucleic acid-based drug production program being pursued by the industry’s leading companies. The addition of new development customers and repeat orders for linear DNA, we believe, suggests a growing appetite for a market-ready alternative to plasmids,” stated Dr. James A. Hayward, president and CEO, Applied DNA.
About Applied DNA Sciences
Applied DNA is a provider of molecular technologies that enable supply chain security, anti-counterfeiting and anti-theft technology, product genotyping, and pre-clinical nucleic acid-based therapeutic drug candidates.
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The Company’s common stock is listed on NASDAQ under ticker symbol ‘APDN’, and its publicly traded warrants are listed on OTC under ticker symbol ‘APPDW’.
Applied DNA is a member of the Russell Microcap® Index.
The statements made by Applied DNA in this press release may be “forward-looking” in nature within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995. Forward-looking statements describe Applied DNA’s future plans, projections, strategies and expectations, and are based on assumptions and involve a number of risks and uncertainties, many of which are