Annovis Bio CEO to Present at Meridian Clinical Trials Summit

BERWYN, Pa., Nov. 02, 2020 (GLOBE NEWSWIRE) — Annovis Bio Inc. (NYSE American: ANVS), a clinical-stage drug platform company addressing Alzheimer’s disease (AD), Parkinson’s disease (PD) and other neurodegenerative diseases, today announced its Founder and CEO, Maria Maccecchini, Ph.D., is presenting at the Meridian Clinical Trials Summit on November 2, 2020 at 10 a.m. ET.

Dr. Maccecchini’s presentation, “De-risking Phase 3 clinical studies in Phase 2; case study from Alzheimer’s and Parkinson’s”, will share insight learned from the Company’s ongoing clinical studies which are measuring all the steps in the toxic cascade leading to nerve cell death and how ANVS401, the Company’s lead compound, might reverse the toxic cascade and recover normal brain function.

“I look forward to sharing with the attendees how I believe we are effectively de-risking our clinical trial programs through our current Phase 2a studies,” commented, Dr. Maccecchini.

About Annovis Bio

Headquartered in Berwyn, Pennsylvania, Annovis Bio, Inc. (Annovis) is a clinical-stage, drug platform company addressing neurodegeneration, such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and Alzheimer’s in Down Syndrome (AD-DS). We believe that we are the only company developing a drug for AD, PD and AD-DS that inhibits more than one neurotoxic protein and, thereby, improves the information highway of the nerve cell, known as axonal transport. When this information flow is impaired, the nerve cell gets sick and dies. We expect our treatment to improve memory loss and dementia associated with AD and AD-DS, as well as body and brain function in PD. We have an ongoing Phase 2a study in AD patients and have commenced a second Phase 2a study in AD and PD patients. For more information on Annovis, please visit the company’s website: www.annovisbio.com.

Forward-Looking Statements

Statements in this press release contain “forward-looking statements” that are subject to substantial risks and uncertainties. Forward-looking statements contained in this press release may be identified by the use of words such as “anticipate,” “expect,” “believe,” “will,” “may,” “should,” “estimate,” “project,” “outlook,” “forecast” or other similar words, and include, without limitation, statements regarding the timing, effectiveness and anticipated results of ANVS401 clinical trials. Forward-looking statements are based on Annovis Bio, Inc.’s current expectations and are subject to inherent uncertainties, risks and assumptions that are difficult to predict. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate, including that clinical trials may be delayed. These and other risks and uncertainties are described more fully in the section titled “Risk Factors” in the Annual Report on Form 10-K for the year ended December 31, 2019 filed with the Securities and Exchange Commission. Forward-looking statements contained in this announcement are made as of this date, and Annovis Bio, Inc. undertakes no duty to update such information except as required under applicable law.

Investor Relations:

Dave Gentry, CEO
RedChip Companies Inc.
407-491-4498
[email protected]

SOURCE: Annovis Bio, Inc.

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CHNC Aims to be the Global Leader in Cannabis Clinical Trials Through a Merger with Pharmacology University

HOUSTON, Texas, Oct. 28, 2020 (GLOBE NEWSWIRE) — via NewMediaWire — CHNC announces its merger with Pharmacology University, Inc., a global leader in the field of medical cannabis education that markets its services under the brand Pharmacology University. More to the point, CHNC joining forces with Pharmacology University Inc. and Precision Research Institute has created one of the most complete companies in the cannabis industry. COO Elizabeth Hernandez explains the reasons behind the decision: “While pursuing my dream, I had wanted to unite forces with a company in the Cannabis Industry and that is when I found Pharmacology University. The synergy between the two companies has been superb and we are positioning ourselves to become the high-end authority of the Cannabis Research Industry. Now this journey finally feels complete. Riding this new wave of inspiration, we are deeply committed to produce revenue generating models and building shareholder value.”

The merger of CHNC, which is publicly traded on OTC markets under the ticker symbol CHNC, provides the framework for Pharmacology University to expand its focus into cannabis clinical trials and bolstering its education offerings.

Founded in 2010, Pharmacology University offers educational products and consulting services in the United States, Puerto Rico, Latin and South America; to train doctors, dispensary owners, growers, lawyers, and other professionals on the palliative and myriad health benefits of cannabis. The company also has partnered with private accredited universities to offer an intensive master’s certification program in cannabis science and is now the top international provider of medical cannabis education.

In addition to its classroom education, Pharmacology University owns and operates Canna Law Magazine, which is a digital informational piece that provides cultural enrichment to the cannabis entrepreneur. The magazine has biweekly editions and informs the public about the most recent legal cases in the cannabis industry worldwide, also providing strategies by which its readers can avoid finding themselves in legal situations for lack of knowledge. Canna Law Magazine is currently available in English, Spanish, Portuguese, Italian and Arabic, and it is being developed to be published in Chinese and Hindi. To view the magazine, visit www.cannalawmagazine.com.

“We want to be pioneers in the search for the truth with actual clinical trials, in regards to how cannabis can be utilized,” says Pharmacology University In-House Legal Counsel, Anne Graham. “Predominantly because the number one problem for people that are set against using cannabis as medicine is simply due to the fact that the cannabis industry has not produced sufficient medical studies,” she says.

The global market for medical cannabis (also known as medical marijuana), is expected to reach more than $150 billion annually by 2027, according to a 2019 report by ResearchAndMarkets.com. The anticipated growth is driven in large part by the legalization of cannabis for medical use in Europe, as well as the passage in the U.S. of the Hemp Farming Act of 2018, which legalized hemp, a variety of the Cannabis Sativa species that has less than 0.3% concentration of tetrahydrocannabinol (THC). And

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Ascendis Pharma A/S Announces Presentations for its Endocrinology Rare Disease Clinical Programs at Upcoming Medical Conferences

COPENHAGEN, Denmark, Oct. 21, 2020 (GLOBE NEWSWIRE) — Ascendis Pharma A/S (Nasdaq: ASND), a biopharmaceutical company that utilizes its innovative TransCon™ technologies to address unmet medical needs, today announced five presentations featuring the company’s endocrinology rare disease programs at two upcoming medical conferences: European Calcified Tissue Society (ECTS) 2020, taking place online October 22–24, 2020, and the Pediatric Endocrinology Nursing Society (PENS) national conference, taking place online November 2–5, 2020.

During ECTS, results from the phase 2 PaTH Forward Trial of TransCon PTH in adult hypoparathyroidism (HP) will be presented. During PENS, data from the phase 3 fliGHt Trial of TransCon hGH (lonapegsomatropin) in pediatric growth hormone deficiency (GHD) and from two clinical trials of the auto-injector for lonapegsomatropin. Additionally, the company will present posters highlighting the impact of achondroplasia (ACH) on the quality of life in children and their parents, which will help inform the TransCon CNP program.

“Ascendis Pharma is committed to supporting the endocrinology community, and we are excited to present data across all three of our endocrinology rare disease programs,” said Aimee Shu, M.D., Senior Medical Director, Clinical Development at Ascendis Pharma. “The data being presented at this year’s ECTS and PENS meetings highlight our portfolio of investigational product candidates and demonstrate important clinical and quality of life outcomes for patients and caregivers, including our first presentation of clinical data on our proprietary auto-injector for lonapegsomatropin.”

Presentation Details

ECTS

Poster Presentation

Title

 

Date/Time

 

Design and Topline Results of TransCon PTH, a Long-acting Parathyroid Hormone (PTH), Phase 2 Trial in Patients with Hypoparathyroidism

 

Presented on Saturday, October 24, 2020 at 4:55–5:00 p.m. (CST) with live Q&A to follow.

 

PENS 2020

Poster Presentations

Title

 

Date/Time

 

Introduction of a Novel GH Auto-Injector for Once-weekly Administration of TransCon hGH (lonapegsomatropin)

 

Posters are available during PENS with live Q&A on Thursday, November 5, 2020 from 2:15–2:45 p.m. (ET).

 

Treatment Experience of Children with Growth Hormone Deficiency in the Phase 3 fliGHt Trial: Switching from Daily Growth Hormone to Once-weekly TransCon hGH (lonapegsomatropin)

 

 

Pediatric Achondroplasia: Impacts on Children’s Functioning and Well-being

 

 

Experiences of Parents of Children with Achondroplasia: Impacts on Quality of Life

 

 

The posters will be available on the Ascendis website under Selected Publications in the Pipeline section: https://ascendispharma.com/product-pipeline/publications/.   If you are a healthcare provider who would like more information, please contact: [email protected]

About TransCon™ Technology Platform

TransCon refers to “transient conjugation.” The proprietary TransCon platform is an innovative technology to create new therapies that are designed to potentially optimize therapeutic effect, including efficacy, safety and dosing frequency. TransCon molecules have three components: an unmodified parent drug, an inert carrier that protects it, and a linker that temporarily binds the two. When bound, the carrier inactivates and shields the parent drug from clearance. When injected into the body, physiologic conditions (e.g., pH and temperature) initiate the release of the active, unmodified parent drug in a predictable manner. Because the parent drug is unmodified, its original mode of action is expected to be maintained. TransCon technologies can be

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