College football odds, picks, predictions for Week 8, 2020: Proven model backing Alabama, Iowa State

The Week 8 college football schedule gets underway on Thursday with Arkansas State at Appalachian State (-10 at William Hill). There are four games on Friday and then the Saturday schedule is highlighted by the return of the Big Ten. It becomes the fourth Power Five conference to begin its season, joining the ACC, Big 12 and SEC. The Pac-12 is scheduled to begin on Nov. 7. 

The Week 8 college football odds from William Hill list No. 5 Ohio State as a 26-point favorite over Nebraska. No. 18 Michigan is laying two points on the road against No. 21 Minnesota. Should you target the Big Ten in your Week 8 college football bets, or do lines in other conferences have more value? Before making any Week 8 college football picks, be sure to see the latest college football predictions from SportsLine’s proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,100 for $100 players on its top-rated college football picks against the spread. It is a sizzling 25-13 on top-rated picks through seven weeks of the 2020 college football season, returning over $700 in profit already. Anybody who has followed it is way up. 

Now, it has turned its attention to the latest college football odds for Week 8 from William Hill and locked in picks for every FBS matchup. Head to SportsLine to see every pick.

Top Week 8 college football predictions 

One of the top Week 8 college football picks the model is recommending: No. 2 Alabama (-20 at William Hill) covers on the road against Tennessee in the 3:30 p.m. ET SEC on CBS matchup. Alabama is coming off an impressive 41-24 victory over then-No. 3 Georgia in Week 7. 

Quarterback Mac Jones and Najee Harris are building Heisman campaigns, while receivers Devonta Smith and Jaylen Waddle will also be a lot to handle for a Tennessee team that stumbles into this matchup after getting blown out 34-7 by Kentucky.

The Vols have huge concerns at quarterback. Jarrett Guarantano hasn’t been able to protect the ball this year and coach Jeremy Pruitt hasn’t committed to him starting. The simulations show Jones throwing for almost 300 yards, with Harris adding around 100 on the ground as Alabama covers well over 60 percent of the time.

Another one of the Week 8 college football predictions from the model: No. 17 Iowa State (+3.5) keeps it within the spread at No. 6 Oklahoma State. After a surprising loss to Louisiana to open the season, the Cyclones have picked up three consecutive wins and covers, including an upset of Oklahoma during that span.

Led by Heisman contender Chuba Hubbard, Oklahoma State is talented, but also relatively untested. The Cowboys haven’t played since Oct. 3 after having their game against Baylor postponed last week. They were sloppy in a season-opening 16-7 win over Tulsa and have only played two Big